PUBLICATION WEBSITES
PatentS & LICENSES
Methods, Systems and Kits for Detecting Protein-Nucleic Acid Interactions.
Pugh BF and Rhee HS. (2011). US Patent. No. 8,367,334 B2
wikipedia
Patent License Agreement between Active Motif and PSU Research Foundation
Pugh BF and Rhee HS. (2012)
Patent License Agreement between Peconic L.L.C. and PSU Research Foundation
Pugh BF and Rhee HS. (2013)
Selected Publications
2023
CREST-Dependent Regulation of Cell Type-Specific Enahncers during Motor Neuron Maturation.
Montanera KN, Yeh S-Y, Ialongo A, and Rhee HS✝. (2023). [PDF]
2022
Extended Intergenic DNA Contributes to Neuron-Specific Expression of Neighboring Genes in the Mammalian Nervous System.
Jaura R*, Yeh S-Y*, Montanera KN, Ialongo A, Anwar Z, Lu Y, Puwakdandawa Loku Acharige K, and Rhee HS✝. (2022). Nature Commun. 13 (1): 2733
*Equally contributed [PDF]
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ChIP-exo Method to Identify Genomic Locations of DNA-Binding Proteins at Near Single Base-Pair Resolution.
Yeh S-Y and Rhee HS✝. (2022). Methods in Mol Biol. 2599:3 3-48 [PDF]
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2020
ChIP-exo: A Method to Study Chromatin Structure and Organization at Near-Nucleotide Resolution.
Montanera KN, Anwar Z, Shibin SM, and Rhee HS✝. (2020). Epigenetics Methods. 18: 323-348. [PDF]
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High-Resolution Mapping of Protein-DNA Interactions in Stem Cell-Derived Neurons Using ChIP-exo.
Montanera KN and Rhee HS✝. (2020). J Vis Exp. 162 (e61124):1-23. [PDF]
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2016
Expression of Terminal Effector Genes in Mammalian Neurons Is Maintained by a Dynamic Relay of Transient Enhancers.
Rhee HS, Closser M, Guo Y, Bashkirova EV, Tan GC, Gifford DK, Wichterle H. (2016). Neuron. 92(6):1252-1265. [PDF]
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Previewed by Sockanathan S. Neuron. 2016 Dec 21;92(6): 1149-1151. [PDF]
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Highlighted by Whalley K. NatRev Neurosci. 2017 Feb;18(2): 70. [PDF]
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2014
Subnucleosomal Structures and Nucleosome Asymmetry across a Genome.
Rhee HS, Bataille AR, Zhang L, Pugh BF. (2014). Cell. 159(6):1377-88. [PDF]
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Previewed by Lieb JD. Cell. 2014 Dec 4;159(6):1249-1251. [PDF]
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A Comprehensive and High-Resolution Genome-Wide Response of p53 to Stress.
Chang GS, Chen XA, Park B, Rhee HS, Li P, Han KH, Mishra T, Chan-Salis KY, Li Y, Hardison RC, Wang Y, Pugh BF. (2014). Cell Rep. 8(2):514-27. [PDF]
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2013
Kinetic Competition between Elongation Rate and Binding of NELF Controls Promoter-Proximal Pausing.
Li J, Liu Y, Rhee HS, Ghosh SK, Bai L, Pugh BF, Gilmour DS. (2013). Mol Cell. 50(5):711-22. [PDF]
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2012
ChIP-exo Method for Identifying Genomic Location of DNA-Binding Proteins with Near-Single-Nucleotide Accuracy.
Rhee HS, Pugh BF. (2012). Curr Protoc Mol Biol. Chapter 21:Unit 21.24. [PDF]
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Genome-Wide Structure and Organization of Eukaryotic Pre-Initiation Complexes.
Rhee HS, Pugh BF. (2012). Nature. 483(7389):295-301. [PDF]
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Previewed by Buratowski S. Nature. 2012 Jan 18;483(7389):286-287. [PDF]
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2011
Comprehensive Genome-Wide Protein-DNA Interactions Detected at Single-Nucleotide Resolution.
Rhee HS, Pugh BF. (2011). Cell. 147(6):1408-19. [PDF]
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Highlighted by Bernstein BE. Genome Biol. 2012 Jan 27;13:139. [PDF]
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Hightlighted by Stower H. NatRev Genet. 2011 Dec 29;13(2):71. [PDF]
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Hightlighted by Nawy T. Nat Methods. 2012 Feb;9(2):130. [PDF]
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2009
Interaction of Transcriptional Regulators with Specific Nucleosomes Across the Saccharomyces Genome.
Koerber RT, Rhee HS, Jiang C, Pugh BF. (2009). Mol Cell. 35(6):889-902. [PDF]
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2006
Fatty Acids, Inhibitors for the DNA Binding of c-Myc/Max Dimer, Suppress Proliferation and Induce Apoptosis of Differentiated HL-60 Human Leukemia Cell.
Jung KC, Park CH, Hwang YH, Rhee HS, Lee JH, Kim HK, Yang CH. (2006). Leukemia. 20(1):122-7. [PDF]
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2005
Momordin I, an Inhibitor of AP-1, Suppressed Osteoclastogenesis through Inhibition of NF-kappa B and AP-1 and also Reduced Osteoclast Activity and Survival.
Hwang YH, Lee JW, Hahm ER, Jung KC, Lee JH, Park CH, Rhee HS, Ryu JM, Kim HK, Yang CH. (2005). Biochem Biophys Res Commun. 337(3):815-23. [PDF]
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Negative Regulation of beta-Catenin/Tcf Signaling by Naringenin in AGS Gastric Cancer Cell.
Lee JH, Park CH, Jung KC, Rhee HS, Yang CH. (2005). Biochem Biophys Res Commun. 335(3):771-6. [PDF]
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Determination of the Dissociation Constants for Recombinant c-Myc, Max, and DNA Complexes: the Inhibitory Effect of Linoleic Acid on the DNA-Binding Step.
Jung KC, Rhee HS, Park CH, Yang CH. (2005). Biochem Biophys Res Commun. 334(1):269-75. [PDF]
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Ionomycin Downregulates beta-Catenin/Tcf Signaling in Colon Cancer Cell Line.
Park CH, Hahm ER, Lee JH, Jung KC, Rhee HS, Yang CH. (2005). Carcinogenesis. 26(11):1929-33. [PDF]
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