Professor Danton H. O'Day's Research

Danton H. O'Day’s current research focusses on the roles of calmodulin and its binding proteins in the onset and progression of neurodegenerative diseases. This area of research holds many keys to understanding them and offering new therapeutic routes for treatment.

As an instructor, Professor O’Day was consistently ranked as excellent by his students. His dedication to communicating important information is reflected in his multiple teaching articles and the classic book “How to Succeed at University” (See: O’Day C.V.).

Recent Publications

(click links to download)

O’Day, D.H., 2025. Tauopathies: Calmodulin Regulates Tau Hyperphosphorylation and Its Transformation into Disease-Specific Aggregates. Biomolecules 15, 1133. https://doi.org/10.3390/biom15081133
O’Day, D. H. 2025. The calmodulin hypothesis of neurodegenerative diseases: searching for a common cure. Neurodegenerative Disease Management, 1–3. https://doi.org/10.1080/17582024.2025.2488230
O’Day, D.H., 2024. The Complex Interplay between Toxic Hallmark Proteins, Calmodulin-Binding Proteins, Ion Channels, and Receptors Involved in Calcium Dyshomeostasis in Neurodegeneration. Biomolecules14, 173. doi: 10.3390/biom14020173
O’Day, D.H., 2024. Calcium and Non-Penetrating Traumatic Brain Injury: A Proposal for the Implementation of an Early Therapeutic Treatment for Initial Head Insults. Biomolecules 2024, 14, 853. doi: 10.3390/biom14070853
O’Day, D.H., 2024. The Search for a Universal Treatment for Defined and Mixed Pathology Neurodegenerative Diseases. Int. J. Mol. Sci. 25, 13424. https://doi.org/10.3390/ijms252413424
O’Day, D.H., 2023. Calmodulin and Amyloid Beta as Coregulators of Critical Events during the Onset and Progression of Alzheimer’s Disease. Int. J. Mol. Sci. 24, 1393. doi: 10.3390/ijms24021393
O'Day, D.H., 2023. Phytochemical Interactions with Calmodulin and Critical Calmodulin Binding Proteins Involved in Amyloidogenesis in Alzheimer’s Disease. Biomolecules 13, 678. doi: 10.3390/biom13040678
O’Day, D.H., 2023. Alzheimer’s Disease beyond Calcium Dysregulation: The Complex Interplay between Calmodulin, Calmodulin-Binding Proteins and Amyloid Beta from Disease Onset through Progression. Curr. Issues Mol. Biol. 45, 6246-6261. doi: 10.3390/cimb45080393
O’Day, D.H., 2023. Protein Biomarkers Shared by Multiple Neurodegenerative Diseases Are Calmodulin-Binding Proteins Offering Novel and Potentially Universal Therapeutic Targets. J. Clin. Med. 12, 7045. doi: 10.3390/jcm12227045

DNA Games

Dan has invented and co-invented multiple educational DNA games including Gene Rummy, Codon and Mutation. They are published and available through Carolina Biological Supply Company, the largest international distributor of educational materials.

Rubaiyat of Omar Khayyam

In addition to publishing multiple books on artists of the Rubaiyat of Omar Khayyam, Dan recently donated the O’Day Rubaiyat Collection of over 350 books to the Library at UTM.

YouTube Videos

Dan has over four dozen videos on his YouTube channel “Danton Canada”. They range from educational and entertaining to animated songs.